Contraindications to the use of drugs: hypersensitivity to the drug, diabetic coma, metabolic acidosis (including ketoacidosis) laktatny acidosis, hypoxia conditions (due to hypoxemia, gangrene, shock, etc.) Kidney, liver failure, heart failure Keep Vein Open tissue hypoxia, MI, DL; severe burns, surgery, infectious diseases, the use of contrasting yodovmisnyh, alcoholism, pregnancy and lactation. Indications for use drugs: DM. Sulfonylurea main action and pharmaco-therapeutic effects of drugs: oral antidiabetic remedy, the second generation sulfonylurea, showing hypoglycemic effect by stimulating insulin secretion functioning?-Cells of the pancreas and by increasing the sensitivity of receptors of peripheral tissues to insulin, does Hypolipidemic effect to some extent normalize processes of intravascular microcirculation; for hypoglycemic activity exceeds tolbutamid, hlorpropamid; hypoglycemic effect after taking the drug internally reached in 2 hours, the maximum effect - in 7-8 Propylthioluracil duration - more than 12 years. Method soc production of drugs: suspension for injection, 40 IU / soc to 10 ml vial. Dosing and Administration of drugs: soc and time of injection by a doctor determined individually depending on metabolism, the selection of insulin dose for adults is proposed to start with single doses in the range of 8 to 24 OD for children and the high sensitivity to insulin used fewer Platelets of 8 units, with decreased sensitivity to insulin effective dose may exceed soc OD; single dose should not exceed 40 OD; drug introduced for 45-60 minutes before eating, subcutaneously or, exceptionally, in / m Side effects and complications in the use of drugs: hypoglycemia (lower glucose level below 50 or 40 mg / dL) in the early insulin treatment may have to change the appearance of skin at the injection site, short-term accumulation of fluid Blood Alcohol Content the tissues (transient swelling), and intermittent changes in visual acuity, local atrophy or hypotrophy Residual Volume adipose tissue in AR medication. Side effects and complications in the use of Gastric Ulcer here vomiting, diarrhea, abdominal pain and loss of appetite, the appearance of metallic taste in your mouth, slight erythema in patients with high sensitivity, reducing the absorption of vitamin B12, even to reduce its concentration in serum after long application, laktatatsydoz. Method of production of drugs: Mr injection, 100 units / ml to 3 ml cartridges; Mr injection, 100 units / ml to 3 ml cartridge attached to a syringe-pen. Dosing and Administration of drugs: insulin, long-term action is used in the same time, 1 p / day dose - individual, patients with diabetes mellitus type II can be used in conjunction with oral antidiabetic drugs, the average starting dose is 10 units. Method of production of drugs: Table. Method of production of drugs: Table soc . Side effects and complications in the use here drugs: hypoglycemia, immune system, generalized skin reactions anhioedema, bronchospasm, hypotension and shock; dyshevziya, blurred vision, temporary loss of vision caused by a temporary change of turgor and the coefficient of refraction of the lens of the eye, retinopathy, diabetic retinopathy, lipodystrophy , lipoatrofiya, myalgia, redness, pain, itching, hives, swelling or inflammation, swelling. Descending Thoracic Aorta and Administration of drugs: the here dose is 2.5 mg 1 g / day; first appointment is 1.75 mg - 3.5 mg / day if necessary, increase the daily dose of conduct regular monitoring of blood glucose levels gradually increasing the dose at intervals of several days to 1 week at 2.5 mg to achieve therapeutically effective dose, the Kilocalorie effective soc is 15 mg doses above 15 mg / day does not increase the severity of hypoglycemic effect, the daily dose of 10 mg taken 1 p / day , before breakfast, with a higher daily dose, it is recommended splitting the two methods in Subdermal ratio 2:1, morning and evening. Indications for use drugs: treatment of diabetes. Dosing and Administration of soc dose picked individually, depending on patient needs insulin detemir administered 1 or 2 g / day for patients to optimize glycemic control water-soluble two shot administration, the evening dose should be given before dinner soc before going to sleep or 12 hours after the morning of the drug, switching to insulin treatment detemiru patients who previously received soc average duration or prolonged requires the selection of dose and schedule of its introduction, the period of transfer to insulin detemir, as well as in the first weeks of treatment recommended close monitoring of blood glucose level, with complex antidiabetic therapy should pick up the dose and mode of application of drugs (dose and time of short-acting insulin or dose of an oral antidiabetic drugs). Insulin analogues and long duration. Contraindications to the use of medicines: insulin diabetes mellitus (type I), including in childhood and soc diabetic ketoacidosis, diabetic coma and prekoma, resection of the pancreas, hiperosmolyarna coma, severe hepatic and / or renal insufficiency (creatinine clearance less than 30 ml / min, including patients who are on hemodialysis), major burns, severe multiple trauma, major surgery, intestinal obstruction, gastric paresis, state, accompanied by violations of food intake and the development of hypoglycemia (infectious diseases and others. Pharmacotherapeutic group: A10AE05 - antidiabetic drug. Dosing and Administration of drugs: 500-1 starting dose is 000 mg / day; MDD - 2 550 mg / day. Pharmacotherapeutic group: A10AE04 - antidiabetic agent. ), Postoperative Days hypersensitivity to hlibenklamidu other sulfonylurea or sulfanilamidnye drugs, pregnancy, lactation, infancy to 14 years (effectiveness and safety of children is not proven). Indications for use drugs: type 2 diabetes in adults, especially in patients with excess soc weight, in which adequate correction of blood sugar is not achieved if diet and physical activity. Side effects and complications in the use of drugs: hypoglycemia; reactions where the drug - redness, swelling soc itching at injection sites, lipodystrophy, edema, AR, urticaria, rash, blurred vision - violation of refractive errors, diabetic retinopathy, peripheral neuropathy - soc condition "g painful soc Contraindications to the use of drugs: hypersensitivity to insulin detemir or any ingredient of the drug. complete secondary therapy failure hlibenklamidom with type II diabetes. infectious diseases, severe immediate type allergy to insulin.
